Burn wound fluid: an important diagnostic source

  • Alan David Widgerow University of California
  • Ilaria Tocco Tussardi University of California
  • Derek A Banyard University of California
  • Kassandra King University of California
  • Ryan Chiang University of California
  • Garrett Wirth University of California
  • Gregory RD Evans University of California
Keywords: burn wound fluid, analysis, diagnostic source

Abstract

Burn wound fluid analysis can be useful in representing the physiological changes taking place in the underlying burn tissue micro-environment. These data may relate to cellular components, signalling mediators and protein content, and can provide clues as to the extent of local tissue damage, the depth of the wound and the potential for systemic complications. This information can impact on wound management decisions, and appears to provide a more accurate reflection of the burn wound pathophysiology than traditional blood or serum investigations. This review provides the historical context of burn fluid analysis, and suggests new avenues for utilising this untapped resource.

Author Biographies

Alan David Widgerow, University of California
MBBCh; FCS (Plast); MMed (Wits); FACS Clinical Professor Director Research and Center for Tissue Engineering Department of Plastic Surgery University of California Irvine
Ilaria Tocco Tussardi, University of California
MD Researcher Center for Tissue Engineering Department of Plastic Surgery University of California Irvine
Derek A Banyard, University of California
MD, MBA Research Fellow Center for Tissue Engineering Department of Plastic Surgery University of California Irvine
Kassandra King, University of California
Researcher Center for Tissue Engineering Department of Plastic Surgery University of California Irvine
Ryan Chiang, University of California
Researcher Center for Tissue Engineering Department of Plastic Surgery University of California Irvine
Garrett Wirth, University of California
MD, MS, FACS Associate Clinical Professor Department of Plastic Surgery University of California Irvine
Gregory RD Evans, University of California
MD, FACS Chairman Department of Plastic Surgery University of California Irvine
Section
General Review